Migraine is one of the most common diseases in the world. About 39 million people in the United States and a billion people worldwide suffer from migraines, or one in every eight men, women, and children living on planet Earth today. Nearly half of all women will experience a migraine at some point in their lives, often between the ages of 35 and 45.
Several treatment options are available, including a combination of preventative and pain-relieving medications. Even some of the infected have turned into narcotic drugs For convenience, which is not surprising when you learn it LSD It was first developed as a vasoconstrictor, a class of medication used to treat migraine headaches.
Cannabis also holds promise as a convenient and effective treatment for pain from migraines and other types of headaches. according to Article review Published in August 2021 by a group of Florida researchers, current evidence indicates that cannabis use “reduces migraine duration and frequency” through the glutamine, inflammatory, opioid and serotonin pathways.1 Two of the 34 studies included in the review are discussed in more detail below.
In addition, two other recently published papers suggest that terpenes, the compounds responsible for the scent of the cannabis plant, may have something to do with this therapeutic effect.
THCHemp flower rich in migraines & headache relief
A study published in the Journal of Integrative Medicine2 In September 2020, inhaling cannabis was found to be highly effective in treating headaches. Researchers at the University of New Mexico drew on more than 2.5 years of data from the digital app Releaf to study real-time links between cannabis use and migraine and headache symptoms. Patients used the app to score pain intensity on a scale of 0 to 10 before and immediately after ingesting cannabis.
Ninety-four percent of users felt symptom relief within two hours of using cannabis, with a decrease in pain intensity of an average of 3.3. Men reported greater relief than women, and patients younger than 35 years of age tended to improve more than older patients. This study found that THC Levels above 10% (as reported by app users according to product labels) were the strongest independent predictor of symptom relief.
Concentrates are more effective than smoked flower
team based at Washington State University (Washington State University) examined archival data from another medical application of cannabis called Strainprint to study the effect of inhaling cannabis on headaches and migraine pain. The researchers also evaluated the effect of gender, cannabis type (flower or concentrate), dose and concentration of cannabis THC And Convention on Biological Diversity on this effect.
After collecting data from thousands of sessions by hundreds of app users, a . file has been created Washington State University The researchers concluded that inhaling cannabis reduced reported headache and migraine pain by nearly half. Their findings were published in May 2021 in The Journal of Pain,3 revealed that the larger cuts were related more to the concentrates than to the flower. The authors also found that men reported greater benefits than women.
However, they also noted a tolerating effect with continued use:[Cannabis’] The effectiveness appears to diminish over time and patients appear to be using larger doses over time.”
Terpene-based drugs for brain health
So what is cannabis that helps improve migraine and headache symptoms? Is it in the first place THCAs the first study suggests? or is THC And Convention on Biological Diversity together, which Other guides What is the best for analgesia of acute pain?
Another factor may be terpenes, the plant compounds that protect and impart flavor and aroma to hemp (and many other plants). Terpenes are increasingly being studied for their therapeutic effect in humans.
In an article published in August 2021 in Frontiers in Psychiatry,4 Australia-based researchers reviewed the evidence for neuropsychiatric benefits associated with two prominent cannabinoids, pinene and linalool. The authors wrote that these compounds affect several neurotransmitter signaling, inflammatory and neurotrophic. Existing data (mostly preclinical, meaning not verified in humans) suggests that migraine is among the conditions—along with stroke, ischemia and other forms of inflammatory pain and neuropathy—that these terpenes may help.
Terpenes prevent neuritis
August 2021 review by Mexican researchers at Frontiers in Pharmacology5 Terpenes are considered anti-inflammatory agents and are evaluating their potential as alternative therapies for encephalitis and dermatitis. The authors wrote that inflammation in the first category is a typical feature of neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease. They also note a recent study by Iranian scholars6 who found an antidepressant-like effect in rats for limonene, another terpene found in several cannabis cultivars, which appeared to be mediated through the inhibition of neuroinflammation.
In what else is neuroinflammation likely to play a role? Migraine. While the authors do not specifically mention headache or migraine in their discussion of terpenes and neuroinflammation, it is an area that warrants further investigation. Taking all these results as a whole, what begins to take shape is a good case of the influence of the surrounding elements as you are likely to find them: THCAnd Convention on Biological Diversity, and at least a handful of terpenes in cannabis are likely to play a role in treating Migraine pain.
Nate Seltenrich, a freelance science journalist based in the San Francisco Bay Area, covers a wide range of topics including environmental health, neuroscience, and pharmacology.
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