Recently published a group of researchers at the University of Chicago study which found that CBD may help prevent the COVID-19 virus in mice and human cells. Scientists believe that CBD interacts with the host’s endoplasmic reticulum and interferon signaling pathways in order to prevent SARS-CoV-2 replication.
Glenn Randall, one of the study’s authors, is a professor in the Department of Microbiology. When starting the research process, Randall mentioned that the team first brainstormed chemicals that could have anti-SARS properties.
“CBD was suggested because it contains anti-inflammatory properties that we thought might dampen the highly aggressive immune response associated with later stages of COVID-19 disease,” Randall said.
During the study, Randall explained, there were a number of surprising findings. “The first surprise was that CBD actually blocks the ability of SARS-CoV-2 to replicate in lung cells and animal models of COVID. It directly activates the genes that our bodies use to fight viral infections.” A second surprise was that patients who were taking the combination FDA-approved CBD used to treat epilepsy had a significantly lower incidence of COVID-19 than comparable patients who did not take CBD.”
In an interview with The Maroon And the Randall described his hopes for the researchers’ next steps. “It is impossible to know the value of CBD in treating or preventing COVID without a carefully designed clinical trial. [UChicago researchers] They are trying to develop such an experience now.”
Randall also stressed that the study findings should not undermine current federal guidelines for COVID-19 prevention. “Neither CBD nor marijuana is an acceptable prevention of COVID at the moment. Vaccines and masking are proven approaches to preventing severe COVID, and CBD should not replace them,” Randall said.
maroon He also spoke with Dr. Thomas Best of the Center for Health and Social Sciences about his work on the study. Best of all, Randall’s surprise was echoed in their results.
“What surprised me in general was that [as] I kept adding more and more checks, or statistical checks and balances, to try to eliminate confusion [evidence]Best said… the association between having a history of CBD and positive testing for COVID remains a significant negative association.”
He learns best from errors in early data, which helped him improve study methods. Before working with the National Covid Cohort Collaborative (N3C), you’d better know that it’s important, “to be careful about the assumptions you make using medical record data. It’s not always clear how the different variables are determined, and one needs to be careful and open about any assumptions they make that might be questionable.”
Best also spoke about the interdisciplinary nature of the study. “There are more authors on this topic than ever before, and the depth of work the team has done is more than I have ever been a part of,” he said. “Different points of view, a number of different experiences [were] Done, both [with] Patients, cytological analysis, mice…. All on one sheet.