Rafael Mechoulam, the first person to synthesize THC, earning him the title “Father of Cannabis Science,” has died. Analytical cannabis reports. He was 92 years old, and his legacy will surely live on for centuries to come. The respected chemist is also called the father of cannabis research. Some of his additional game-changing contributions to pharmacology include the isolation and synthesis of other cannabinoids, such as cannabidiol (CBD), cannabigrel (CBG), and cannabinoids (CBC).
While THC, CBD, and CBG are basically household names today, this wouldn’t be the case if it weren’t for Dr. Meshulam, so smoke one for him on the anniversary. A professor of medicinal chemistry at the Hebrew University of Jerusalem in Israel, his work laid the foundation and got the ball (or sharp) for future breakthroughs, such as lighting up endogenous cannabinoid receptors in the human body in the 1980s and 1990s, as detailed in a 1993 academic paper titled Molecular characterization of peripheral cannabinoid receptors.
Make sure to be respected today, as do Dr. Meshulam’s friends and fellow scientists, as you pass the Peace Pipe with your buddies. “This is a very sad day for me, the science community and the cannabis community. Professor Raphael Meshulam or as we call him Ravi was one of the greatest scientists[s] I met you one day and you were my teacher and mentor in many aspects. I really believe in it [deserved] Nobel prize! David “Didi” Miri, associate professor at the Technion, Israel Institute of Technology, and Meshulam colleagues, wrote in a poignant letter. Online statement. “Thank you Ravi for all the wonderful things you did and discovered[ed] In your life and thanks for all the help and support you have given me. Rest in peace my dear friend,” he continues.
Born in Sofia, Bulgaria, in 1930, Meshulam and his family moved to Israel, where he began studying chemistry. His inspiration to start a successful hunt for THC began after judicious observation of the mechanisms of other drugs. in an interview With CNN in 2014Mechoulam noted: “Morphine was isolated from opium in the nineteenth and early nineteenth centuries, and cocaine from coca leaves.” [in the] Mid nineteenth century. And here we are in the middle of the 20th century, and yet the chemistry of cannabis was unknown. So it seemed [an] Interesting project. According to the National Library of Medicine, in 1964, he succeeded. And the story behind how Meshullam obtained the cannabis he studied might surprise you.
While working as a chemist in the early 1960s at the Weizmann Institute, Meshulam got some weed from the Israeli police with his goal already: discovering and isolating what makes pot psychoactive. Once THC and other cannabinoids, such as the aforementioned CBD and CBG, were identified in 1992, Discover Meshulam and his team The chemical arachidonoyl ethanolamine, which you know as anandamide (derived from the Sanskrit word Ananda, which means bliss). Anandamide is something that our body’s endocannabinoid system produces on its own (as if we were designed to use cannabis) and activates the CB1 receptor.
Passionate and deeply industrious, Meshulam continued his research until his death. At the age of 88, at the CannMed Cannabis Conference in California in 2019, he announced another breakthrough, synthetically stable. Cannabidiolic acid (CBDA), the main plant cannabinoid in fiber and hemp oil, which has anti-inflammatory, anti-spasmodic, and anti-cancer properties, and this is probably just the tip of the iceberg. “We have taken unstable acid molecules from the cannabis plant and synthesized them to provide a stable and consistent basis for the search for new therapies across a wide range of medical needs.” Meshulam explained at the conference. He also used his time on the stage to encourage the scientific community to invest more in cannabis research, enough time already being lost, citing several people from the past who would have benefited greatly from medical cannabis if it had been available. “Should we have waited 30 years? No,” he said. “We could have helped thousands of children, but we didn’t.”
Rest in power, Dr. Meshulam, and may everyone fortunate enough to have access to the results of his work enjoy the power of botanical medicine today.